Bio-Techne Corporation is proud to announce that Lunaphore, a Bio-Techne brand, will be showcasing their groundbreaking spatial biology technologies at the highly anticipated 2023 conference. This event will feature presentations by renowned research centers, highlighting the unmatched capabilities of Lunaphore's COMET™ platform. By addressing complex biological questions, Lunaphore is revolutionizing cancer therapy approaches and immune response characterization. Let's delve into the details of this exciting development in the field of spatial biology.
Unmatched Spatial Biology Capabilities
Explore the cutting-edge spatial biology capabilities of Lunaphore's COMET™ platform
Lunaphore's COMET™ platform is revolutionizing spatial biology by offering unmatched capabilities in addressing complex biological questions. Unlike other hyperplex solutions, COMET™ is fully automated, high-throughput, and does not require the conjugation of primary antibodies. This unique feature allows for flexible and faster panel design, making it the go-to solution for researchers.
With the ability to analyze up to 40 spatial markers in each automated run, COMET™ provides researchers with highly robust and reproducible data. Its scalability and reproducibility make it a valuable tool in various research areas, including cancer therapy and immune response characterization.
Characterizing the Tumor Microenvironment
Discover how Lunaphore's COMET™ platform is used to characterize the tumor microenvironment
Lunaphore's COMET™ platform has been instrumental in characterizing the tumor microenvironment (TME) in response to various treatments. Researchers have used the hyperplex-based approach to study the immune response to combined immunotherapy and stereotactic ablative radiation therapy (iSABR) neoadjuvant treatment of head and neck squamous cell carcinoma (HNSCC).
By leveraging the power of COMET™, researchers have been able to develop rapid hyperplex sequential immunofluorescence (seqIF™) panels and optimize high-throughput data analytics. This novel approach provides unprecedented insights into the immune compartment and has the potential to enhance the clinical success of cancer therapies.
Mapping Immune and Tumoral Cells
Learn how Lunaphore's COMET™ platform is used to map immune and tumoral cells in various cancer tissues
Lunaphore's COMET™ platform, in combination with off-the-shelf antibodies, has enabled researchers to map immune and tumoral cells in lymphomas and various cancer tissues. The seqIF™ approach allows for a comprehensive analysis of the immune landscape, providing valuable insights into the tumor microenvironment.
Researchers have been able to visualize and analyze the expression of specific biomarkers, shedding light on the interactions between immune cells and tumor cells. This information is crucial for understanding disease progression and developing targeted therapies.
Multiomics Analysis of the Tumor Microenvironment
Discover the proof-of-concept COMET™ workflow for multiomics analysis of the tumor microenvironment
Lunaphore has demonstrated a proof-of-concept workflow for same-slide, fully automated multiomics analysis of the tumor microenvironment using the COMET™ platform. This innovative approach integrates RNA in situ hybridization and sequential immunofluorescence to obtain comprehensive insights into the molecular and cellular composition of the TME.
By combining these two powerful techniques, researchers can analyze gene expression patterns and spatially resolve protein markers simultaneously. This workflow has the potential to revolutionize our understanding of the TME and accelerate the development of personalized therapies.
Live Demonstrations and Access to Raw Staining Images
Visit Lunaphore's booth for live demonstrations of the COMET™ system and access to raw staining images
If you're attending the conference, don't miss the opportunity to visit Lunaphore's booth (#530). Their scientists will be available to provide live demonstrations of the COMET™ system, showcasing its capabilities and answering any questions you may have.
In addition, Lunaphore will also provide access to raw staining images of various cancer types. This unique opportunity allows researchers to get a firsthand look at the high-quality data generated by the COMET™ platform and explore its potential applications in their own research.
Conclusion
Lunaphore's presence at the 2023 conference has showcased the groundbreaking capabilities of their COMET™ platform in the field of spatial biology. With its fully automated, high-throughput, and label-free approach, COMET™ is revolutionizing the way researchers study the tumor microenvironment and characterize immune responses.
The ability to map immune and tumoral cells, perform multiomics analysis, and obtain high-quality data has opened up new possibilities for understanding disease pathology and developing personalized therapies. Lunaphore's commitment to innovation and collaboration is driving advancements in spatial biology and bringing us closer to improved patient outcomes.
FQA
What makes Lunaphore's COMET™ platform unique?
Lunaphore's COMET™ platform stands out for its fully automated, high-throughput capabilities and the flexibility of using off-the-shelf antibodies. This allows for faster panel design and greater scalability without the need for antibody conjugation.
How does COMET™ contribute to cancer therapy research?
COMET™ enables researchers to characterize the tumor microenvironment and study the immune response to different treatments. This information is crucial for developing innovative anti-cancer therapy approaches and improving treatment outcomes.
What are the potential applications of COMET™ in spatial biology?
COMET™ has a wide range of applications in spatial biology, including mapping immune and tumoral cells, performing multiomics analysis, and studying the molecular and cellular composition of the tumor microenvironment. These capabilities provide valuable insights for understanding disease progression and developing targeted therapies.
Where can I learn more about Lunaphore and their products?
To learn more about Lunaphore and their innovative spatial biology solutions, please visit their website or reach out to their team at the 2023 conference. They will be available for live demonstrations and to provide access to raw staining images.
